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LNA-mediated microRNA silencing in non-human primates

Authors :
Elmen, Joacim
Lindow, Morten
Schutz, Sylvia
Lawrence, Matthew
Petri, Andreas
Obad, Susanna
Lindholm, Marie
Hedtjarn, Maj
Hansen, Henrik Frydenlund
Berger, Urs
Gullans, Steven
Kearney, Phil
Sarnow, Peter
Straarup, Ellen Marie
Kauppinen, Sakari
Source :
Nature. April 17, 2008, Vol. 452 Issue 7189, p896, 5 p.
Publication Year :
2008

Abstract

microRNAs (miRNAs) are small regulatory RNAs that are important in development and disease (1-3) and therefore represent a potential new class of targets for therapeutic intervention (4). Despite recent progress [...]

Details

Language :
English
ISSN :
00280836
Volume :
452
Issue :
7189
Database :
Gale General OneFile
Journal :
Nature
Publication Type :
Academic Journal
Accession number :
edsgcl.189748565