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Proteomic analysis of active multiple sclerosis lesions reveals therapeutic targets

Authors :
Han, May H.
Hwang, Sun-Il
Roy, Dolly B.
Lundgren, Deborah H.
Price, Jordan V.
Ousman, Shalina S.
Fernald, Guy Haskin
Gerlitz, Bruce
Robinson, William H.
Baranzini, Sergio E.
Grinnell, Brian W.
Raine, Cedric S.
Sobel, Raymond A.
Han, David K.
Steinman, Lawrence
Source :
Nature. February 28, 2008, Vol. 451 Issue 7182, p1076, 8 p.
Publication Year :
2008

Abstract

Understanding the neuropathology ofmultiple sclerosis (MS) is essential for improved therapies. Therefore, identification of targets specific to pathological types of MS may have therapeutic benefits. Here we identify, by laser-capture [...]

Details

Language :
English
ISSN :
00280836
Volume :
451
Issue :
7182
Database :
Gale General OneFile
Journal :
Nature
Publication Type :
Academic Journal
Accession number :
edsgcl.189705177