Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes

Authors :: Xin Yuan
Waterworth, Dawn
Perry, John R.B.
Lim, Noha
Kijoung Song
Chambers, John C.
Weihua Zhang
Vollenweider, Peter
Stirnadel, Heide
Johnson, Toby
Bergmann, Sven
Beckmann, Noam D.
Yun Li
Ferrucci, Luigi
Melzer, David
Hernandez, Dena
Singleton, Andrew
Scott, James
Elliott, Paul
Waeber, Gerard
Cardon, Lon
Frayling, Timothy M.
Kooner, Jaspal S.
Mooser, Vincent
Source :: American Journal of Human Genetics. Oct 10, 2008, Vol. 83 Issue 4, p520, 9 p.
Publication Year :: 2008
Abstract: The article discusses the results obtained from several different population-based genome-wide association studies of the plasma liver-enzyme levels in three different populations. The analysis reveals six loci that influence the plasma levels, hence providing candidate genes for several liver diseases.

Subjects :: Blood plasma -- Genetic aspects
Liver diseases -- Genetic aspects
Liver diseases -- Physiological aspects
Population genetics -- Research
Genetic transcription -- Analysis
Biological sciences

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