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Autophagy in thymic epithelium shapes the T-cell repertoire and is essential for tolerance
- Source :
- Nature. September 18, 2008, Vol. 455 Issue 7211, p396, 6 p.
- Publication Year :
- 2008
-
Abstract
- Recognition of self-antigen-derived epitopes presented by major histocompatibility complex class II (MHC II) molecules on thymic epithelial cells (TECs) is critical for the generation of a functional and self-tolerant CD4 [...]
- Subjects :
- Epithelium -- Research -- Physiological aspects -- Usage
T cells -- Research -- Physiological aspects -- Usage
Animal models in research -- Usage -- Research -- Physiological aspects
Antigens -- Research -- Physiological aspects -- Usage
Environmental issues
Science and technology
Zoology and wildlife conservation
Physiological aspects
Usage
Research
Subjects
Details
- Language :
- English
- ISSN :
- 00280836
- Volume :
- 455
- Issue :
- 7211
- Database :
- Gale General OneFile
- Journal :
- Nature
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.188943144