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T-cell-expressed proprotein convertase furin is essential for maintenance of peripheral immune tolerance

Authors :
Pesu, Marko
Watford, Wendy T.
Wei, Lai
Xu, Lili
Fuss, Ivan
Strober, Warren
Andersson, John
Shevach, Ethan M.
Quezado, Martha
Bouladoux, Nicolas
Roebroek, Anton
Belkaid, Yasmin
Creemers, John
O'Shea, John
Source :
Nature. September 11, 2008, Vol. 455 Issue 7210, p246, 7 p.
Publication Year :
2008

Abstract

Furin is one of seven proprotein convertase family members that promote proteolytic maturation of proproteins (1). It is induced in activated T cells and is reported to process a variety [...]

Details

Language :
English
ISSN :
00280836
Volume :
455
Issue :
7210
Database :
Gale General OneFile
Journal :
Nature
Publication Type :
Academic Journal
Accession number :
edsgcl.188899779