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Unexpected solvent-free cycloadditions of 1,3-cyclohexanediones to 1-(pyridin-2-yl)-enones mediated by manganese(III) acetate in a ball mill
Unexpected solvent-free cycloadditions of 1,3-cyclohexanediones to 1-(pyridin-2-yl)-enones mediated by manganese(III) acetate in a ball mill
- Source :
- Journal of Organic Chemistry. Sept 19, 2008, Vol. 73 Issue 18, 7088-7095
- Publication Year :
- 2008
-
Abstract
- Manganese(III) acetate dihydrate-mediated cycloadditions of 5,5-dimethyl-1,3-cyclohexanedione and 1,3-cyclohexanedione to various 1-(pyridine-2-yl)-enones to obtain trans-2-acyl-3-aryl/alkyl-2,3,6,7-tetrahydro-4(5H)-benzofuranone derivatives is reported. The cyclization reaction carried out under solvent-free ball-milling conditions exhibited good to excelled yields with extremely high diastereoselectivity and unexpected regioselectivity.
Details
- Language :
- English
- ISSN :
- 00223263
- Volume :
- 73
- Issue :
- 18
- Database :
- Gale General OneFile
- Journal :
- Journal of Organic Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.188011780