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Thin-film microbiosensors for glucose-lactate monitoring
- Source :
- Analytical Chemistry. Sept 15, 1996, Vol. 68 Issue 18, p3173, 7 p.
- Publication Year :
- 1996
-
Abstract
- A miniaturized device for simultaneous measurement of glucose and lactate levels was produced by means of photopatterning of enzyme-containing photosensitive membrane precursors. This device shows no cross-talk and a lifetime for both the glucose and the lactate sensors of more than 2 weeks when continuously operated in undiluted bovine serum. Linear response ranges of up to 40 mM for glucose and 25 mM for L-lactate, in combination with 95% response times of 0.98 with respect to laboratory techniques. Subcutaneous measurements of glucose levels in pigs were close to the corresponding blood levels obtained without in vivo calibration.
- Subjects :
- Biosensors -- Design and construction
Thin films -- Usage
Chemistry
Subjects
Details
- ISSN :
- 00032700
- Volume :
- 68
- Issue :
- 18
- Database :
- Gale General OneFile
- Journal :
- Analytical Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.18772061