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Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs

Authors :
Soutschek, Jurgen
Akinc, Akin
Bramlage, Birgit
Charisse, Klaus
Constien, Rainer
Donoghue, Mary
Elbashir, Sayda
Geick, Anke
Hadwiger, Philipp
Harborth, Jens
John, Matthias
Kesavan, Venkitasamy
Lavine, Gary
Pandey, Rajendra K.
Racie, Timothy
Rajeev, Kallanthottathil G.
Rohl, Ingo
Toudjarska, Ivanka
Wang, Gang
Wuschko, Silvio
Bumcrot, David
Koteliansky, Victor
Limmer, Stefan
Manoharan, Muthiah
Vornlocher, Hans-Peter
Source :
Nature. November 11, 2004, Vol. 432 Issue 7014, p173, 6 p.
Publication Year :
2004

Abstract

Author(s): Jürgen Soutschek (corresponding author) [1]; Akin Akinc [2]; Birgit Bramlage [1]; Klaus Charisse [2]; Rainer Constien [1]; Mary Donoghue [2]; Sayda Elbashir [2]; Anke Geick [1]; Philipp Hadwiger [1]; [...]

Details

Language :
English
ISSN :
00280836
Volume :
432
Issue :
7014
Database :
Gale General OneFile
Journal :
Nature
Publication Type :
Academic Journal
Accession number :
edsgcl.186287764
Full Text :
https://doi.org/10.1038/nature03121