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Gabapentin, valproic acid, and ethanol intoxication: elevated blood levels with mild clinical effects

Authors :
Fernandez, Miguel C.
Walter, Frank G.
Petersen, Lizabeth R.
Walkotte, Steven M.
Source :
Journal of Toxicology: Clinical Toxicology. July, 1996, Vol. 34 Issue 4, p437, 3 p.
Publication Year :
1996

Abstract

Case Report: A suicidal, epileptic patient ingested ethanol, valproic acid, and gabapentin, a new antiepileptic drug. He did well clinically despite elevated blood gabapentin, valproic acid, and ethanol. Conclusions: Preliminary data from this case and one previous report indicate relatively mild clinical signs and symptoms with gabapentin poisoning.<br />INTRODUCTION In 1993 the FDA approved gabapentin (GBP) as add-on therapy for adults with unsatisfactory control of partial seizures.[1] To date, five GBP overdoses have been published but only one [...]

Details

ISSN :
07313810
Volume :
34
Issue :
4
Database :
Gale General OneFile
Journal :
Journal of Toxicology: Clinical Toxicology
Publication Type :
Periodical
Accession number :
edsgcl.18602545