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Two forms of the nucleoside diphosphate kinase of Pseudomonas aeruginosa 8830: altered specificity of nucleoside triphosphate synthesis by the cell membrane-associated form of the truncated enzyme
- Source :
- Journal of Bacteriology. April, 1996, Vol. 178 Issue 7-8, p1777, 5 p.
- Publication Year :
- 1996
-
Abstract
- An intracellular protease was found to cleave the 16-kDa form of nucleoside diphosphate kinase (Ndk) in Pseudomonas aeruginosa to a 12-kDa form that undergoes autophosphorylation with an efficiency almost similar to that of the 16-kDa form. The 12 kDa-form of Ndk synthesizes GTP in preference to other nucleoside triphosphates. The generation of the 12-kDa form of Ndk and its association with the cell membrane are linked to the growth stage of P. aeruginosa.
Details
- ISSN :
- 00219193
- Volume :
- 178
- Issue :
- 7-8
- Database :
- Gale General OneFile
- Journal :
- Journal of Bacteriology
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.18507209