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The prion's elusive reason for being

Authors :
Aguzzi, Adriano
Baumann, Frank
Bremer, Juliane
Source :
Annual Review of Neuroscience. Annual, 2008, Vol. 31, 439-477
Publication Year :
2008

Abstract

The article explains the traits and effects of the various diseases that are caused by the improper behavior of the prion protein in humans. The different physiological functions of the normal cellular protein, Pr[P.sup.c] are shown to lead to the several toxic phenotypes that are observed in the prion disease.

Details

Language :
English
ISSN :
0147006X
Volume :
31
Database :
Gale General OneFile
Journal :
Annual Review of Neuroscience
Publication Type :
Academic Journal
Accession number :
edsgcl.184207964