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Effect of the air-water interface on the structure of lysozyme in the presence of guanidinium chloride

Authors :
Perriman, Adam W.
Henderson, Mark J.
Evenhuis, Christian R.
McGillivray, Duncan J.
White, John W.
Source :
Journal of Physical Chemistry B. August 7, 2008, Vol. 112 Issue 31, 9532-9539
Publication Year :
2008

Abstract

The changes in the surface structure of lysozyme adsorbed at the air-water interface produced by the chemical denaturant guanidinium chloride are examined. The methodologies to predict the protein orientation at the interface, based on amino acid residues' surface affinities and charge, are validated.

Details

Language :
English
ISSN :
15206106
Volume :
112
Issue :
31
Database :
Gale General OneFile
Journal :
Journal of Physical Chemistry B
Publication Type :
Academic Journal
Accession number :
edsgcl.184096160