Gastric emptying of ingested fat emulsion in rats: implications for studies of fat-induced satiety

The mode of fat intake has been shown to determine eating behavior in rats. Herein, the effect of gastrointestinal infusion of fat on eating behavior was compared to that produced when fat is ingested. Gastric emptying was measured and used as a function of fat-induced satiety. Results showed that gastrointestinal infusion of fat produces immediate satiety as compared to ingestion. Ingestion of fat emulsion was suggested to cause increases in food intake because it is not immediately satiating.