UME6 is a central component of a developmental regulatory switch controlling meiosis-specific gene expression

Authors :: Steber, Camille M.
Esposito, Rochelle Easton
Source :: Proceedings of the National Academy of Sciences of the United States. Dec 19, 1995, Vol. 92 Issue 26, p12490, 5 p.
Publication Year :: 1995
Abstract: A study was conducted to examine the role of the UME6 gene of Saccharomyces cerevisiae in sporulation and meiosis-specific gene expression. S1 nuclease protection assays showed that UME6 encodes a Zn2Cys6 DNA-binding protein which binds to cis-acting element URS1. The complete deletion of UME6 caused the vegetative derepression of meotic genes during vegetative growth and a reduction in induction of meiosis-specific genes.

Subjects :: Genetic regulation -- Research
Meiosis -- Genetic aspects
Yeast -- Genetic aspects
Science and technology

ISSN :: 00278424
Volume :: 92
Issue :: 26
Database :: Gale General OneFile
Journal :: Proceedings of the National Academy of Sciences of the United States
Publication Type :: Academic Journal
Accession number :: edsgcl.18090830

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