Charge transfer in the K proton pathway linked to the catalytic site in cytochrome c oxidase

An experiment was designed to investigate electrogenic reactions in the structural variants of the cytochrome c oxidase, where in the residues in the second, K proton pathway of cytochrome c oxidase, were modified. The results indicated that the electrogenic reaction associated with the electron transfer to the catalytic sites originates as a result of charge transfer within the K pathway.