Efflux of cellular cholesterol and phospholipid to lipid-free apolipoproteins and class A amphipathic peptides

Authors :: Yancey, Patricia G.
Bielicki, John K.
Johnson, William J.
Lund-Katz, Sissel
Palgunachari, Mayakonda N.
Anantharamaiah, G.M.
Segrest, Jere P.
Phillips, Michael C.
Rothblat, George H.
Source :: Biochemistry. June 20, 1995, Vol. 34 Issue 24, p7955, 11 p.
Publication Year :: 1995
Abstract: Protein/phospholipid complexes are formed during the first interaction of apolipoprotein (apo) AI or similar peptides with cells, and cholesterol efflux follows. Cholesterol and phospholipid efflux increased by 12- and 4-fold respectively from cholesterol-enriched mouse macrophages when compared to cells not loaded with cholesterol.

Subjects :: Cholesterol metabolism -- Research
Apolipoproteins -- Research
Biological sciences
Chemistry

Tools