Electrocatalytically driven omega-hydroxylation of fatty acids using cytochrome P450 4A1

Authors :: Faulkner, Kevin M.
Shet, Manjunath S.
Fisher, Charles W.
Estabrook, Ronald W.
Source :: Proceedings of the National Academy of Sciences of the United States. August 15, 1995, Vol. 92 Issue 17, p7705, 5 p.
Publication Year :: 1995
Abstract: Electrolytic systems containing a platinum electrode and a redox mediator with purified recombinant proteins containing P450A1 are applicable to various P450s for the synthesis of stereo and regio-specific hydroxylated products. Experimental results show that NADPH can be replaced by these systems for the electrocatalytically mediated omega-hydroxylation of lauric acid.

Subjects :: Electrochemistry -- Usage
Hydroxylation -- Analysis
Fatty acids -- Research
Cytochrome P-450 -- Usage
Science and technology

ISSN :: 00278424
Volume :: 92
Issue :: 17
Database :: Gale General OneFile
Journal :: Proceedings of the National Academy of Sciences of the United States
Publication Type :: Academic Journal
Accession number :: edsgcl.17943933

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