FISH mapping of de novo apparently balanced chromosome rearrangements identifies characteristics associated with phenotypic abnormality

Authors :: Fantes, J.A.
Boland, E.
Ramsay, J.
Donnai, D.
Splitt, M.
Goodship, J.A.
Stewart, H.
Whiteford, M.
Gautier, P.
Harewood, L.
Holloway, S.
Sharkey, F.
Maher, E.
van Heyningen, V.
Clayton-Smith, J.
Fitzpatrick, D.R.
Black, G.C.M.
Source :: American Journal of Human Genetics. April, 2008, Vol. 82 Issue 4, p916, 11 p.
Publication Year :: 2008
Abstract: The study employs the fluorescence in situ hybridization (FISH) mapping technique to analyze the de novo, apparently the balanced chromosome rearrangements (ABCR) for determining the various characteristics that leads to phenotypic abnormality in humans.

Subjects :: Chromosome abnormalities -- Research
Chromosome mapping -- Analysis
Fluorescence -- Usage
Human genome -- Research
Biological sciences

Tools