Variability in expression of antigens responsible for serotype specificity in Candida albicans

A study conducted on the expression of the antigens, serotype A and B, of Candida albicans shows that the serotype A is more reactive in acidic medium while serotype B is more reactive in alkaline medium. Indirect immunofluorescence shows that the monoclonal antibody B9E and the polyclonal monospecific antiserum against the antibody 6 in vitro react with the cell walls of the serotype A yeast cells but not with serotype B. However spectrofluorometry shows similar reactivity of both the serotypes.