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Purification of IgM monoclonal antibodies: manufacturing challenges surround the use of IgM monoclonal antibodies, but these can be overcome with current technology
- Source :
- Biopharm International. March, 2008, Vol. 21 Issue 3, p26, 10 p.
- Publication Year :
- 2008
-
Abstract
- ABSTRACT The affinity capture paradigm that dominates industrial IgG purification has proven unsuitable for IgMs because, in most cases, they are affected adversely by harsh elution conditions. The large size [...]
- Subjects :
- Proteins -- Denaturation
Protein binding
Biological products
Immunoglobulins
Anion exchangers (Biology)
Hydroxides
Sodium sulfate
Sodium citrate
Proteolysis
Bookbinding
Glycol ethers
Ammonium sulphate
Polyacrylamide
Monomers
Metastasis
Industrial productivity
Hydroxylapatite
Monoclonal antibodies
Glycols
Questions and answers
Aluminum compounds
Productivity
Biotechnology industry
Business
Pharmaceuticals and cosmetics industries
Subjects
Details
- Language :
- English
- ISSN :
- 1542166X
- Volume :
- 21
- Issue :
- 3
- Database :
- Gale General OneFile
- Journal :
- Biopharm International
- Publication Type :
- Periodical
- Accession number :
- edsgcl.177589666