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Neuropathy target esterase gene mutations cause motor neuron disease

Authors :
Rainier, Shirley
Bui, Melanie
Mark, Erin
Thomas, Donald
Tokarz, Debra
Lei Ming
Delaney, Colin
Richardson, Rudy J.
Albers, James W.
Matsunami, Nori
Stevens, Jeff
Coon, Hilary
Leppert, Mark
Fink, John K.
Source :
American Journal of Human Genetics. March, 2008, Vol. 82 Issue 3, p780, 6 p.
Publication Year :
2008

Abstract

Several genome-wide analyses are conducted to explain the connection of the organophosphorus (OP) compounds with the motor neuron disease (MND). The MND is caused by the neuropathy target esterase (NTE) that is usually inhibited by the OP compounds.

Details

Language :
English
ISSN :
00029297
Volume :
82
Issue :
3
Database :
Gale General OneFile
Journal :
American Journal of Human Genetics
Publication Type :
Academic Journal
Accession number :
edsgcl.177045453