The artificial 4-zinc-finger protein Bagly binds human utrophin promoter A at the endogenous chromosomal site and activates transcription

Authors :: Onori, Annalisa
Desantis, Agata
Buontempo, Serena
Di Certo, Maria Grazia
Fanciulli, Maurizio
Salvatori, Luisa
Passananti, Claudio
Corbi, Nicoletta
Source :: Biochemistry and Cell Biology. June 2007, Vol. 85 Issue 3, p358, 8 p.
Publication Year :: 2007
Abstract: Abstract: Our aim is to upregulate the expression of the dystrophin-related gene utrophin in Duchenne muscular dystrophy, in this way complementing the lack of dystrophin function. To achieve utrophin upregulation, [...]

Subjects :: Zinc finger proteins -- Physiological aspects -- Genetic aspects
Utrophin -- Genetic aspects -- Physiological aspects
Genetic transcription -- Evaluation -- Genetic aspects -- Physiological aspects
DNA binding proteins -- Genetic aspects -- Physiological aspects
Biological sciences
Evaluation
Physiological aspects
Genetic aspects

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