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Identification of two flavivirus-like genomes in the GB hepatitis agent

Authors :
Simons, John N.
Pilot-Matias, Tami J.
Leary, Thomas P.
Dawson, George J.
Desai, Suresh M.
Schlauder, George G.
Muerhoff, A. Scott
Erker, James C.
Buijk, Sheri L.
Chalmers, Michelle L.
Van Sant, Charles L.
Mushahwar, Isa K.
Source :
Proceedings of the National Academy of Sciences of the United States. April 11, 1995, Vol. 92 Issue 8, p3401, 5 p.
Publication Year :
1995

Abstract

Representational difference analysis, used to clone nucleotide sequences present in the plasma from a tamarin infected with the GB hepatitis agent reveals the presence of flavivirus-like genomes in the GB agent. Flaviviruses are viruses that are enveloped and contain one positive-sense genomic RNA molecule. The two viruses may have different origins, one may have the human GB as its source, while the other probably originates from tamarins during the passage of the GB agents in tamarins.

Details

ISSN :
00278424
Volume :
92
Issue :
8
Database :
Gale General OneFile
Journal :
Proceedings of the National Academy of Sciences of the United States
Publication Type :
Academic Journal
Accession number :
edsgcl.17626789