Age at menarche among diethylstilbestrol granddaughters

Granddaughters of women who took diethylstilbestrol (DES) during pregnancy may not experience delays in the age of first menstruation. Researchers followed up a group of women who had been exposed to DES before they had been born, and their 123 daughters who were over 10 years old. The daughters of the women exposed to DES experienced their first menstrual period at about the same age, 12.7 years, as daughters of women who had not been exposed to DES. DES may not change the age of sexual maturity among granddaughters of women who received DES. The influence of DES on other aspects of health is unknown but is being researched.