Ontogeny of endothelial nitric oxide synthase mRNA in an ovine model of fetal and placental growth restriction

To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.ajog.2007.07.016 Byline: Bradley T. Ziebell (a), Henry L. Galan (a), Russell V. Anthony (b), Timothy R.H. Regnault (b), Thomas A. Parker (b), Juan A. Arroyo (a) Keywords: endothelial nitric oxide synthase; IUGR; ontogeny Abstract: To determine: 1) placental eNOS mRNA concentration across gestation in normal ovine pregnancy and in an ovine model of intrauterine growth restriction (IUGR), and 2) placental eNOS protein concentration in early ovine pregnancy. Author Affiliation: (a) Division of Perinatal Medicine, Department of Obstetrics & Gynecology, University of Colorado at Denver and Health Sciences Center, Denver, CO (b) Division of Perinatal Medicine, Department of Pediatrics, University of Colorado at Denver and Health Sciences Center, Denver, CO. Article History: Received 13 March 2007; Revised 20 June 2007; Accepted 16 July 2007 Article Note: (footnote) Supported by grant R01 HL071990-01A1 from the National Institutes of Health., Cite this article as: Ziebell BT, Galan HL, Anthony RV, et al. Ontogeny of endothelial nitric oxide synthase mRNA in an ovine model of fetal and placental growth restriction. Am J Obstet Gynecol 2007;197:420.e1-420.e5.