The oxidation potential of adenosine and adenosine-thymidine base pair in chloroform solution

Voltammetric methods are used for studying the oxidation potential of 2',3'-O-isopropylidene-5'-O-(tert-butyldimethylsilyl)adenosine and its change upon pairing with the complementary base thymidine in chloroform. The studies have shown that Hoogsteen and Watson-Crick association modes are of comparable stability in solution and have displayed similar oxidation potential in chloroform.