Highly enantioselective Henry (nitroaldol) reaction of aldehydes and [alpha]-ketoesters catalyzed by N,N'-dioxide-copper(I) complexes

Authors :: Bo Qin
Xiao Xiao
Xiaohua Liu
Jinglun Huang
Yuehong Wen
Xiaoming Feng
Source :: Journal of Organic Chemistry. Nov 23, 2007, Vol. 72 Issue 24, 9323-9328
Publication Year :: 2007
Abstract: A new chiral N,N'-dioxide-Cu catalyst is developed for the asymmetric Henry (nitroaldol) reaction and is used for catalyzing [alpha]-ketoesters. This mechanism has described the origin of reactivity and asymmetric inductivity.

Subjects :: Organocuprates -- Chemical properties
Aldehydes -- Chemical properties
Catalysis -- Research
Enantiomers -- Chemical properties
Nuclear magnetic resonance spectroscopy -- Technology application
Technology application
Biological sciences
Chemistry

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