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The central melanocortin system directly controls peripheral lipid metabolism

Authors :
Nogueiras, Ruben
Wiedmer, Petra
Perez-Tilve, Diego
Veyrat-Durebex, Christelle
Keogh, Julia M.
Sutton, Gregory M.
Pfluger, Paul T.
Castaneda, Tamara R.
Neschen, Susanne
Hofmann, Susanna M.
Howles, Philip N.
Morgan, Donald A.
Benoit, Stephen C.
Szanto, Ildiko
Schrott, Brigitte
Schurmann, Annette
Joost, Hans-Georg
Hammond, Craig
Hui, David Y.
Woods, Stephen C.
Rahmouni, Kamal
Butler, Andrew A.
Farooqi, I. Sadaf
O'Rahilly, Stephen
Rohner-Jeanrenaud, Francoise
Tschop, Matthias H.
Source :
Journal of Clinical Investigation. Nov, 2007, Vol. 117 Issue 11, p3475, 14 p.
Publication Year :
2007

Abstract

Disruptions of the melanocortin signaling system have been linked to obesity. We investigated a possible role of the central nervous melanocortin system (CNS-Mcr) in the control of adiposity through effects [...]

Details

Language :
English
ISSN :
00219738
Volume :
117
Issue :
11
Database :
Gale General OneFile
Journal :
Journal of Clinical Investigation
Publication Type :
Academic Journal
Accession number :
edsgcl.171774003