Back to Search Start Over

Preferential fragmentation of protonated gas-phase peptide ions adjacent to acidic amino acid residues

Authors :
Qin, Jun
Chait, Brian T.
Source :
Journal of the American Chemical Society. May 17, 1995, Vol. 117 Issue 19, p5411, 2 p.
Publication Year :
1995

Abstract

A study of fragmentation of 25 protonated peptide ions in quadrupole ion trap mass spectrometer by matrix-assisted laser desorption/ionization shows that cleavages adjacent to acidic residues are prominent in fragmentation. Observation of preferential fragmentation adjacent to glutamic acid residues shows selective fragementation at Asp and Glu.

Details

ISSN :
00027863
Volume :
117
Issue :
19
Database :
Gale General OneFile
Journal :
Journal of the American Chemical Society
Publication Type :
Academic Journal
Accession number :
edsgcl.17132865