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Radial glial cell transformation to astrocytes is bidirectional: regulation by a diffusible factor in embryonic forebrain

Authors :
Hunter, Kim E.
Hatten, Mary E.
Source :
Proceedings of the National Academy of Sciences of the United States. March 14, 1995, Vol. 92 Issue 6, p2061, 5 p.
Publication Year :
1995

Abstract

Extrinsic soluble signals in embryonic forebrain are crucial for the expression of embryonic radial glial identity. Radial glial characteristics are reexpressed by astrocytes in vitro in the presence of embryonic cortical signals and in vivo following transplantation into embryonic neocortex. Thus, inducing signals are vital for the transformation of radial glia cells into astrocytes.

Details

ISSN :
00278424
Volume :
92
Issue :
6
Database :
Gale General OneFile
Journal :
Proceedings of the National Academy of Sciences of the United States
Publication Type :
Academic Journal
Accession number :
edsgcl.17102146