Injection of bone marrow mesenchymal stem cells in the borderline area of infarcted myocardium: Heart status and cell distribution

To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.jtcvs.2007.07.019 Byline: Hao Zhang (a), Peng Song (a), Yue Tang (b), Xiao-ling Zhang (a), Shi-hua Zhao (c), Ying-jie Wei (a), Sheng-shou Hu (a) Abbreviations: BM, bone marrow; IMI, intramyocardial injection; MI, myocardial infarction; MRI, magnetic resonance imaging; MSCs, mesenchymal stem cells; qRT-PCR, quantitative real-time polymerase chain reaction; SRY, Y-chromosome gene Abstract: This study aimed to test the distribution of intramyocardially injected cells in variations in heart status in a porcine model of myocardial infarction. Author Affiliation: (a) Research Center for Cardiac Regenerative Medicine, the Ministry of Health and Department of Surgery, Fu Wai Hospital, Beijing, China (b) Animal Research Center, Fu Wai Hospital, Beijing, China (c) Unit of Magnetic Resonance Imaging, Fu Wai Hospital, Beijing, China. Article History: Received 19 April 2007; Revised 25 June 2007; Accepted 19 July 2007 Article Note: (footnote) Supported by the National Eleven-Five Year Project (S.H), National Scientific Foundation of China (30500498) and Beijing Nova Project (2006A85) (H.Z).