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Nucleolipoplexes: a new paradigm for phospholipid bilayer-nucleic acid interactions

Authors :
Milani, Silvia
Bombelli, Francesca Baldelli
Berti, Debora
Baglioni, Piero
Source :
Journal of the American Chemical Society. Sept 26, 2007, Vol. 129 Issue 38, 11664-11665
Publication Year :
2007

Abstract

An ordered lamellar phase of type [L.sub.[alpha].sup.c] is formed without any mediation from divalent cations in order to study nucleic acid/nucleolipid complexes. Polynucleotides bind to small like-charged globular micelles and this behavior is present even in different suprastructures as bilayer membranes from long-chain derivatives.

Details

Language :
English
ISSN :
00027863
Volume :
129
Issue :
38
Database :
Gale General OneFile
Journal :
Journal of the American Chemical Society
Publication Type :
Academic Journal
Accession number :
edsgcl.169941896