Back to Search Start Over

Synthesis of polysubstituted imidazo[1,2-a]pyridines via microwave-assisted one-pot cyclization/Suzuki coupling/palladium-catalyzed heteroarylation

Authors :
Koubachi, Jamal
Kazzouli, Said El
Berteina-Raboin, Sabine
Mouaddib, Abderrahim
Guillaumet, Gerald
Source :
Journal of Organic Chemistry. Sept 28, 2007, Vol. 72 Issue 20, p7650, 6 p.
Publication Year :
2007

Abstract

A microwave-assisted one-pot, two-step or one-pot, three-step cylization/Suzuki/heteroarylation method was developed to synthesize the 2,3,6-trisubstituted imidazo[1,2-a]pyridine derivatives. The newly developed method could be applied to obtain other polysubstituted compounds from 2-amino-5-halogenopyridines, 2-halogenocarbonyl derivatives, boronic acids and heteroaryl bromides.

Details

Language :
English
ISSN :
00223263
Volume :
72
Issue :
20
Database :
Gale General OneFile
Journal :
Journal of Organic Chemistry
Publication Type :
Academic Journal
Accession number :
edsgcl.169894804