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Paclitaxel-functionalized gold nanoparticles

Authors :
Gibson, Jacob D.
Khanal, Bishnu P.
Zubarev, Eugene R.
Source :
Journal of the American Chemical Society. Sept 19, 2007, Vol. 129 Issue 37, 11653-11661
Publication Year :
2007

Abstract

The synthesis of paclitaxel-gold nanoparticles hybrid structures is described and standard analytical methods are used for observing the covalent attachment of paclitaxel molecules to the surface of 2 nm gold nanocrystals. This approach has provided an opportunity for preparing hybrid particles with a well-defined amount of drug and has offered a new alternative for the design of nanosized drug-delivery systems.

Details

Language :
English
ISSN :
00027863
Volume :
129
Issue :
37
Database :
Gale General OneFile
Journal :
Journal of the American Chemical Society
Publication Type :
Academic Journal
Accession number :
edsgcl.169706934