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Enhanced hypothalamic-pituitary-adrenocortical axis responses to physostigmine in normal aging

Authors :
Peskind, Elaine R.
Raskind, Murray A.
Wingerson, Dane
Pascualy, Marcella
Thal, Leon J.
Dobie, Dorcas J.
Veith, Richard C.
Dorsa, Daniel M.
Murray, Sharon
Sikkema, Carl
Galt, Stephen A.
Wilkinson, Charles W.
Source :
The Journals of Gerontology, Series A. March, 1995, Vol. 50 Issue 2, pM114, 7 p.
Publication Year :
1995

Abstract

A comparative study of the pharmacologic responses of hypothalamic-pituitary-adrenocortical (HPA) axis to physostigmine, a cholinesterase inhibitor, in younger and older adults indicates that aging enhances HPA axis response to physostigmine. There is no variation in the levels of physostigmine in the plasma due to aging.

Subjects

Subjects :
Hypothalamic-pituitary-adrenal axis -- Research
Aging -- Physiological aspects
Physostigmine -- Physiological aspects
Health
Seniors

Details

ISSN :
10795006
Volume :
50
Issue :
2
Database :
Gale General OneFile
Journal :
The Journals of Gerontology, Series A
Publication Type :
Academic Journal
Accession number :
edsgcl.16956609

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