Membrane mobility and microdomain association of the dopamine transporter studied with fluorescence correlation spectroscopy and fluorescence recovery after photobleaching

Authors :: Samuvel, Devadoss J.
Adkins, Erika M.
Fog, Jacob U.
Eriksen, Jacob
Jayanthi, Lankupalle D.
Ramamoorthy, Sammanda
Gether, Ulrik
Vaegter, Christian Bjerggaard
Source :: Biochemistry. Sept 18, 2007, Vol. 46 Issue 37, 10484-10497
Publication Year :: 2007
Abstract: The article investigates the association of the dopamine transporter (DAT) with lipid microdomains in the plasma membrane and the cytoskeleton. The findings propose that the association serves to regulate both the lateral mobility of the transporter and its transport capacity.

Subjects :: Dopamine -- Analysis
Cell membranes -- Analysis
Cytoskeleton -- Analysis
Biological sciences
Chemistry

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