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A QM/MM study of the Bergman reaction of dynemicin A in the minor groove of DNA

Authors :
Tuttle, Tell
Kraka, Elfi
Thiel, Walter
Cremer, Dieter
Source :
Journal of Physical Chemistry B. July 19, 2007, Vol. 111 Issue 28, 8321-8328
Publication Year :
2007

Abstract

The QM/MM investigation results of the Bergmann cyclization of the natural enediyne dynemicin A in its triggered form bound to the minor groove of DNA is reported.

Details

Language :
English
ISSN :
15206106
Volume :
111
Issue :
28
Database :
Gale General OneFile
Journal :
Journal of Physical Chemistry B
Publication Type :
Academic Journal
Accession number :
edsgcl.167834692