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Toll-like receptor 2 impairs host defense in gram-negative sepsis caused by Burkholderia pseudomallei (melioidosis)

Authors :
Wiersinga, W. Joost
Wieland, Catharina W.
Dessing, Mark C.
Chantratita, Narisara
Cheng, Allen C.
Limmathurotsakul, Direk
Chierakul, Wirongrong
Leendertse, Masja
Florquin, Sandrina
de Vos, Alex F.
White, Nicholas
Dondorp, Arjen M.
Day, Nicholas P.
Peacock, Sharon J.
van der Poll, Tom
Source :
PLoS Medicine. July, 2007, Vol. 4 Issue 7, p1268, 13 p.
Publication Year :
2007

Abstract

ABSTRACT Background Toll-like receptors (TLRs) are essential in host defense against pathogens by virtue of their capacity to detect microbes and initiate the immune response. TLR2 is seen as the [...]

Details

Language :
English
ISSN :
15491277
Volume :
4
Issue :
7
Database :
Gale General OneFile
Journal :
PLoS Medicine
Publication Type :
Academic Journal
Accession number :
edsgcl.167628117