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CmaE: A transferase shuttling aminoacyl groups between carrier protein domains in the coronamic acid biosynthetic pathway

Authors :
Strieter, Eric R.
Vaillancourt, Frederic H.
Walsh, Christopher T.
Source :
Biochemistry. June 26, 2007, Vol. 46 Issue 25, 7549-7557
Publication Year :
2007

Abstract

CmaE is a commonly used transferase, which helps in moving the aminoacyl groups between various carrier protein domains in the coronamic acid biosynthetic pathway. The analysis shows that CmaE can also be used for generating chemical diversity within a nonribosomalpeptide (NRPS).

Details

Language :
English
ISSN :
00062960
Volume :
46
Issue :
25
Database :
Gale General OneFile
Journal :
Biochemistry
Publication Type :
Academic Journal
Accession number :
edsgcl.167498432