Development of a Nazarov cyclization/Wagner-Meerwein rearrangement sequence for the stereoselective synthesis of spirocycles

Authors :: Jie Huang
Frontier, Alison J.
Source :: Journal of the American Chemical Society. July 4, 2007, Vol. 129 Issue 26, p8060, 2 p.
Publication Year :: 2007
Abstract: A Nazarov cyclization/Wagner-Meerwein rearrangement pathway that produces unusual spirocyclic products is described. The transformations are found to be highly stereoselective, efficient for a range of substrate types and are capable of creating adjacent quaternary centers.

Subjects :: Ring formation (Chemistry) -- Analysis
Rearrangements (Chemistry) -- Analysis
Stereoisomers -- Chemical properties
Chemistry

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