Cloning and molecular characterization of three arylamine N-acetyltransferase genes from bacillus anthracis: Identification of unusual enzymatic properties and their contribution to sulfamethoxazole resistance

Authors :: Pluvinage, Benjamin
Dairou, Julien
Possot, Odile M.
Martins, Marta
Fouet, Agnes
Dupret, Jean-Marie
Rodrigues-Lima, Fernando
Source :: Biochemistry. June 12, 2007, Vol. 46 Issue 23, p7069, 10 p.
Publication Year :: 2007
Abstract: A report is presented on cloning, functional expression and characterization of three new N-acetyltransferases (NATs) genes from the pathogen Bacillus anthracis. The three NAT homologues exhibit distinct structural and enzymatic properties.

Subjects :: Aromatic amines -- Structure
Aromatic amines -- Chemical properties
Bacillus anthracis -- Genetic aspects
Bacillus anthracis -- Research
Drug resistance in microorganisms -- Research
Transferases -- Structure
Transferases -- Chemical properties
Biological sciences
Chemistry

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