Gab family proteins are essential for postnatal maintenance of cardiac function via neuregulin-1/ErbB signaling

Authors :: Nakaoka, Yoshikazu
Nishida, Keigo
Narimatsu, Masahiro
Kamiya, Atsunori
Minami, Takashi
Sawa, Hirofumi
Okawa, Katsuya
Fujio, Yasushi
Koyama, Tatsuya
Maeda, Makiko
Sone, Manami
Yamasaki, Satoru
Arai, Yuji
Koh, Gou Young
Kodama, Tatsuhiko
Hirota, Hisao
Otsu, Kinya
Hirano, Toshio
Mochizuki, Naoki
Source :: Journal of Clinical Investigation. July, 2007, Vol. 117 Issue 7, p1771, 11 p.
Publication Year :: 2007
Abstract: Grb2-associated binder (Gab) family of scaffolding adaptor proteins coordinate signaling cascades downstream of growth factor and cytokine receptors. In the heart, among EGF family members, neuregulin-1[beta] (NRG-1[beta], a paracrine factor [...]

Subjects :: Cytokine receptors -- Research
Heart -- Research
Oncogenes -- Research
Proteins -- Research
Erythrocytes -- Research

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