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Rhythmic control of AANAT translation by hnRNP Q in circadian melatonin production

Authors :
Tae-Don Kim
Kyong-Tai Kim
Kyung-Chul Woo
Sunghan Cho
Dae-Cheong Ha
Sung Key Jang
Source :
Genes & Development. April 1, 2007, Vol. 21 Issue 7, p797, 4 p.
Publication Year :
2007

Abstract

The expression of AANAt protein is up regulated at night by rhythmic translation of AANAT mRNA by highly conserved IRES (internal ribosome entry site) element. This is essential for the circadian production of pineal melatonnin.

Details

Language :
English
ISSN :
08909369
Volume :
21
Issue :
7
Database :
Gale General OneFile
Journal :
Genes & Development
Publication Type :
Academic Journal
Accession number :
edsgcl.165773588