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A novel multicomponent reaction of arynes, [beta]-keto sulfones, and Michael-type acceptors: A direct synthesis of polysubstituted naphthols and naphthalenes
- Source :
- Journal of Organic Chemistry. May 11, 2007, Vol. 72 Issue 10, p3965, 4 p.
- Publication Year :
- 2007
-
Abstract
- A novel multicomponent reaction of arynes, [beta]-keto sulfones and Michael-type acceptors has provided an efficient method for the synthesis of polysubstituted naphthols and polysubstituted naphthalenes. It is shown that the tandem reaction might proceed via a sequential nucleophilic attack to arynes, intramolecular nucleophilic substitution followed by a Michael addition and a ring closure-elimination process.
Details
- Language :
- English
- ISSN :
- 00223263
- Volume :
- 72
- Issue :
- 10
- Database :
- Gale General OneFile
- Journal :
- Journal of Organic Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.165764620