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Palmitic acid is absorbed as sn-2 monopalmitin from milk and formula with rearranged triacylglycerols and results in increased plasma triglyceride sn-2 and cholesteryl ester palmitate in piglets
- Source :
- The Journal of Nutrition. Jan, 1995, Vol. 125 Issue 1, p73, 9 p.
- Publication Year :
- 1995
-
Abstract
- Milk fatty acids contain 20-30% palmitic acid (16:0), with [approximately] 70% of the 16:0 esterified to the sn-2 position of the milk triacylglycerol. Formulae containing vegetable and oleo oils contain different amounts of 16:0, but all have unsaturated fatty acids esterified to the triacylglycerol sn-2 position. Intraluminal triacylglycerol hydrolysis by endogenous lipases produces sn-2 monoacylglycerols and free fatty acids, which are absorbed and re-esterified in the enterocyte for secretion to plasma. The extent of absorption and re-esterification of sn-2 monoacylglycerols from milk or formula fats in infants is unknown. This was studied by feeding piglets sow milk or formulae containing similar total saturated fat, 18:1, 18:2(n-6) and 18:3(n-3) with unsaturated fatty acids at the sn-2 position or with rearranged triacylglycerols containing -30% 16:0, with 70% 16:0 in fatty acids at the sn-2 position. Feeding milk or 16:0 on the sn-2 position of formula with rearranged triacylglycerols resulted in higher 16:0 esterified to the plasma triacylglycerol sn-2 position and in cholesteryl esters than feeding formulae with 0.4 to 4.4% 16:0 in the sn-2 position fatty acids. The absorption of 16:0 as monopalmitin from milk and any metabolic importance in human infants has yet to be determined. INDEXING KEY WORDS: milk triacylglycerols; monoacylglycerol; infant formula; palmitic acid; absorption; piglets
Details
- ISSN :
- 00223166
- Volume :
- 125
- Issue :
- 1
- Database :
- Gale General OneFile
- Journal :
- The Journal of Nutrition
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.16566677