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Effects of cardiac glycosides on myocardial function and energetics in conscious dogs

Authors :
Lucke, John C.
Elbeery, Joseph R.
Koutlas, Theodore C.
Gall, Stanley A., Jr.
D'Amico, Thomas A.
Maier, George W.
Rankin, J. Scott
Glower, Donald D.
Source :
The American Journal of Physiology. Nov, 1994, Vol. 267 Issue 5, pH2042, 8 p.
Publication Year :
1994

Abstract

Analysis of the physiological effects of intravenous ouabin on left ventricular systolic function and metabolic-to-mechanical energy transfer in conscious dogs reveals the significant positive ionotropic effect of ouabin on the intact left ventricle. Ouabin enhances the myocardial performance and energetics in dogs without oxygen washing or changes in energy transfer efficiency.

Details

ISSN :
00029513
Volume :
267
Issue :
5
Database :
Gale General OneFile
Journal :
The American Journal of Physiology
Publication Type :
Academic Journal
Accession number :
edsgcl.16557324