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A simple and improved correction for population stratification in case-control studies
- Source :
- American Journal of Human Genetics. May, 2007, Vol. 80 Issue 5, p921, 10 p.
- Publication Year :
- 2007
-
Abstract
- Available approaches for controlling stratification by use of substructure-informative loci is not able to resolve the population stratification in case-control studies of disease-marker association hence, a new two-step procedure is proposed to address the issue. This two-step procedure approach yields a more appropriate correction for stratification than the principal components or genomic control.
Details
- Language :
- English
- ISSN :
- 00029297
- Volume :
- 80
- Issue :
- 5
- Database :
- Gale General OneFile
- Journal :
- American Journal of Human Genetics
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.163989538