Proton-coupled electron transfer in a biomimetic peptide as a model of enzyme regulatory mechanisms

A newly designed amino acid sequence containing one tyrosine residue is employed to study and describe the various proton-coupled electron-transfer reactions in a biomimetic peptide, which are often used as a model for the study of the enzyme regulatory mechanisms in proteins. The results of the analysis show that the thermodynamic coupling increases the yield of the tyrosyl radical at low pH by stabilizing it due to the interstrand [pi]-cation interaction.