Back to Search Start Over

Covalent catalysis by pyridoxal: Evaluation of the effect of the cofactor on the carbon acidity of glycine

Authors :
Toth, Krisztina
Richard, John P.
Source :
Journal of the American Chemical Society. March 14, 2007, Vol. 129 Issue 10, p3013, 9 p.
Publication Year :
2007

Abstract

A study determines the first-order rate constants for deprotonation of the [alpha]-amino carbon of the adduct between 5'-deoxypyridoxal and glycine. No significant deprotonation is found at pH 7.1 of the form of the 1-glycine iminium ion with the pyridine nitrogen in the basic form.

Details

Language :
English
ISSN :
00027863
Volume :
129
Issue :
10
Database :
Gale General OneFile
Journal :
Journal of the American Chemical Society
Publication Type :
Academic Journal
Accession number :
edsgcl.163173508