Calorie restriction increases muscle mitochondrial biogenesis in healthy humans

Authors :: Civitarese, Anthony E.
Carling, Stacy
Heilbronn, Leonie K.
Hulver, Mathew H.
Ukropcova, Barbara
Deutsch, Walter A.
Smith, Steven R.
Ravussin, Eric
Source :: PLoS Medicine. March, 2007, Vol. 4 Issue 3, p485, 10 p.
Publication Year :: 2007
Abstract: ABSTRACT Background Caloric restriction without malnutrition extends life span in a range of organisms including insects and mammals and lowers free radical production by the mitochondria. However, the mechanism responsible [...]